Board Thread:Questions and Answers/@comment-27617248-20160115214910/@comment-6697950-20160119153657

And where in the anime did you hear anyone say that the AmuSphere can interact with anything other than the brain itself? Also, where in the anime did you hear anyone say that the brain is capable of measuring blood nutrient levels? Because otherwise, the AmuSphere can only detect what the brain knows or what its sensors can pick up.

The AmuSphere does have sensors for detecting heart rate, body temperature and other such things (though I'm not sure if the AmuSphere actually uses non-cerebral sensors or just monitors the respective control centres in the medulla oblongata and hypothalamus), but how do you propose for it to detect how well the user is nourished? It could monitor brain centres responsible for hunger, but those centres can be confused by eating virtual food, thus the brain is convinced that food was eaten when none actually was. It doesn't have any sensors inside the body, so it can't detect blood content and I don't know of any way for a machine to measure it externally.

But since the AmuSphere can actually monitor level of consciousness, heart rate etc., it can log the user out if an abnormality in any of these arises because of malnourishment.